50% chance of rain today

Hi readers! This is my second promised, the devil is in the detail, post focusing on MND/ALS research. Hot on the heels of placebo ethics, I now take on the highly complementary subject of statistics: how they are presented, their meaning and finally how they can/can’t be used in research. This is a big post, and as…

Can placebo trials ever be justified for terminal illness diseases……?

Hi readers, onein300 here with my latest MND Research commentary post. The title is a question I see occasionally posed on social media, disease community discussion groups and in the wider news. It most certainly is a conundrum. Jumping to an emotional conclusion should be avoided. Before you read on I want to point out…

The trials and tribulations of coy scientists

Welcome, to my first research opinion post of 2019 on the hunt for an effective treatment for MND. “About time!” I hear you cry. Calm down, readers. I have been deep in thought and wanted to give you something worth sitting down with a nice cup of coffee to enjoy. This stuff doesn’t write itself,…

Weapon of Choice Too!

Good day all. Here is Dr Peter Scott-Morgan’s promised guest post as part of MND Awareness Month here in the UK. A provocative article on the challenges we all might face and the pioneering research he is undertaking. His post is about choices that we could take that, as Peter himself often says, will help us…

Weapon of Choice?

A nice mysterious title for a research opinion post? Read on, my intrigued and loyal followers….

One thing leads to another – MND Research Opinion update – March 2018

I have just realised that I haven’t written a onein400 research opinion post for over 6 months! Apologies, readers. Let me correct this right now! This one is split into two distinct sections. First, a quick, but timely, update about the pipeline for new drugs/treatments and then a discussion about genetics and the rather indistinct…

Chain reaction – ‘MND caused by Genetics, time and “what”?’

“I’m in the middle of a chain reaction!” – the words of Diana Ross written by Barry, Maurice and Robin Gibb. As part of MND awareness month I am writing a couple of special posts. This one has the rather clumsy subtitle – MND caused by genetics, time and what?” What is this what?!

My view on the current road to a therapy – Jan 2017 Update

Here are my current observations on the move towards for what we all want, and that is an effective therapy for MND/ALS. This post is based on reading papers including symposium abstracts. No more, no less. I am a very optimistic person, but at the same time I temper my thoughts with realism and the rigours…

My view September 2016

I have been meaning to post this research update for a while, but once I started writing it, I knew I had to think it out carefully. I maintain a page on Research, which you may like to take a read of before reading this update. Today I want to give my perspective on where…

Chocolate Biscuits – Does genetics hold the key to MND/ALS?

Arhh an interesting and be-musing title. Read on viewers to gain insight into the inner workings of my mind. You will have to wait a bit for the biscuits, however. I finished my last post asking the question when does the disease start? The general consensus is that it is a combination of genetics, time,…