50% chance of rain today

Hi readers! This is my second promised, the devil is in the detail, post focusing on MND/ALS research. Hot on the heels of placebo ethics, I now take on the highly complementary subject of statistics: how they are presented, their meaning and finally how they can/can’t be used in research. This is a big post, and as…

Can placebo trials ever be justified for terminal illness diseases……?

Hi readers, onein300 here with my latest MND Research commentary post. The title is a question I see occasionally posed on social media, disease community discussion groups and in the wider news. It most certainly is a conundrum. Jumping to an emotional conclusion should be avoided. Before you read on I want to point out…

Rules are made to be broken?

Hi, readers! Another few weeks in onein400 land have passed. I apologise for the recent ‘radio silence’. The good weather and organised chaos have kept me from quill and ink! But now I am back! Settle down with your last remaining Easter eggs (some half price ones are still available in the stores!), enjoy another…

Times they are a changin….

Or are they? This week’s theme, to weave into my everyday life, is one of those loose phrases that is often both true and false. Of course, it’s also a classic Bob Dylan song. More from the legendary Bob later but, in the meantime, on with my epistle produced during the recent UK snow! I…

13 days Later…

Welcome to 2019 readers! My post is a little bit late. Thirteen days late to be precise. I decided to let all of you get back into the real swing of things before penning my first strange, but often entirely true, musings of the year. Has the New Year reset, and perhaps, purified the whole of humanity?…

1981 – A Vintage London Fairy Tale

The year is 1981. It is 5.40pm and Lord Lee Bragg, in his Soho Office, is just tidying up his papers after a long trying, yet invigorating, Christmas Eve working day. He is about to set off for Waterloo Station heading home……

Get a grip!

Hi, readers! Get a grip! What do I mean, my loyal subscribers? Read on, into the mystical, yet strangely, totally believable world of onein400…..

That was the summer that was – Part 1

Wow, what a summer! Perfect weather, and time spent with great friends. Best weather since 1976, which I actually remember quite well. So what’s been happening? During my self-imposed exile from the blog over summer, the world has provided plenty of inspiration, through daily events, crazy stories, but above all from the stupidity of the…

Weapon of Choice Too!

Good day all. Here is Dr Peter Scott-Morgan’s promised guest post as part of MND Awareness Month here in the UK. A provocative article on the challenges we all might face and the pioneering research he is undertaking. His post is about choices that we could take that, as Peter himself often says, will help us…